Mutations in HIV-1 Reverse Transcriptase and Protease Associated with Drug Resistance
نویسندگان
چکیده
The knowledge of HIV-1 drug resistance continues to increase at an exponential rate. This is particularly true for resistance to HIV-1 protease inhibitors, for which the first resistant variants were described less than two years ago (Otto et al., PNAS 90:7453–7457, 1993). Now resistance to virtually all classes of protease inhibitors has been documented. To keep our readership informed of newly described mutations, we have updated the tables below, which first appeared in IAVN in May 1994 (Vol 2; No 5). Following the tables is a list of abbreviations used. We hope that the tables’ revised content will be useful to virologists and clinicians active in the field. We urge all investigators to provide additions or amendments of the table to any of the authors. Data formatted as in the table with an appropriate reference (abstract, manuscripts or paper) would be welcomed.
منابع مشابه
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